Beilstein J. Org. Chem.2017,13, 1388–1395, doi:10.3762/bjoc.13.135
experimental challenges aimed at constructing protocell systems made of a diversity of functionally coupled components and, thereby, at characterizing more precisely the type of prebiotic evolutionary dynamics that such protocells could engage in.
Keywords: functionalintegration; origins of life; prebiotic
move the field of origins of life forward would be to couple simple chemistry to prebiotic vesicle dynamics: chemical reactions provide the power for endogenous synthesis and vesicles the adequate scaffolding for the functionalintegration of what is synthesized. We will proceed briefly with the issue
of functionalintegration below, but the main point to highlight here is that both for reactive processes to become proto-metabolic and for vesicles to become proto-cellular, their mutual, dynamic engagement could well be an early, unavoidable requirement [40].
As Szostak [41] has also noted, the
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Figure 1:
Protocells as the main units of prebiotic evolution: three hypothetical stages of development towar...